IndraLab

Statements

BAP1 inhibits PRC2_complex. 2 / 2

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"Loss of BAP1 has been shown to be synthetically lethal with inhibition of EZH2 or PRC2."

30030490

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"As for the reported tumor suppressive mechanism, BAP1 can antagonize EZH2 and PRC2 or RING1B (RNF2)/PRC1 in a tissue specific manner."

32269030

INDRA sources:

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IndraLab

Statements

BAP1 inhibits PRC2_complex. 2 / 2

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