IndraLab

Statements

Calcium(2+) activates CACNA1D. 3 / 3
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"The expression of functionally different splice isoforms of Ca V 1.2 and Ca V 1.3 in different tissues enables Cacna1c and Cacna1d genes to support a wider range of calcium dependent cellular functions [XREF_BIBR, XREF_BIBR, XREF_BIBR - XREF_BIBR]."
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"IGF-1 can rapidly activate CaV1.3 by modulating IGF-1R, which phosphorylates and activates CaMKII (CaV1.3a and CaV1.3b at the C termini sites, resulting in inositol trisphosphate (IP3)-induced Ca release [181]."
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"However, the increase in LCR triggered by Ca 2+ entry through Cav1.3 and Cav 3.1 at the late phase of CL masks the mitochondrial contribution."
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