IndraLab

Statements

TRIM39 binds CALM1. 3 / 3
| 3
sparser
"TFP binds to CALM in a Ca 2+ -dependent manner ( xref ), which induces tertiary structure change of CALM from an elongated dumb-bell, with exposed hydrophobic surfaces, to a compact spherical structure that no longer interacts with its target enzymes ( xref ; xref )."
36386620
sparser
"It has been reported that the binding of TFP and CALM changes the affinity of CALM for Ca 2+ ( xref ; xref )."
36386620
sparser
"It is reasonable to speculate that the binding of TFP to CALM not only changes the affinity of CALM for Ca 2+ , but also changes the Ca 2+ concentration in cells, which consequently destroying the ER Ca 2+ homeostasis."
36386620