IndraLab

Statements


SID1900 inhibits KCNK2. 2 / 2
| 2

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"Electrophysiological research has shown that SID1900 and the previously reported TREK1 blocker (spadin) efficiently blocked TREK-1 current in HEK293 cells and specifically blocked two-pore domain potassium channels in primary cultured rat hippocampal neurons."

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"The small molecule SID1900 was found to inhibit TREK-1 with an IC50 of 29.72 μM, comparing that of spadin is 40 nM [40]."