IndraLab

Statements

CHUK phosphorylates CYLD on S418. 4 / 4
1 | 2 1
reach
"Previous work demonstrated that TNF-alpha induces IKKalpha- and IKKbeta mediated serine phosphorylation of CYLD (Ser 418) [49]."
20347313
signor
"Thus, serine 418 is phosphorylated in vivo. Cyld phosphorylation may serve as a mechanism to inactivate its traf2 deubiquitination activity."
24614225
reach
"While it has been reported that IKKalpha and IKKbeta can phosphorylate Ser418 of CYLD, we demonstrated that CYLD is phosphorylated much more efficiently by IKKepsilon than by either of the canonical IKKs."
19481526
sparser
"While it has been reported that IKKα and IKKβ can phosphorylate Ser418 of CYLD ( xref ), we demonstrated that CYLD is phosphorylated much more efficiently by IKKε than by either of the canonical IKKs."
19481526