IndraLab

Statements

Hydroxyzine inhibits KCNH2. 4 / 4
1 | 3
reach
"The results suggest that hydroxyzine could block hERG channels and prolong APD."
21892192
ctd
No evidence text available
19057127
reach
"Hydroxyzine was found to block peak hERG channel tail currents in a concentration dependent manner, with an IC 50 of 0.39 mumol/L at near-physiological temperature (n = 4; Fig."
28480041
reach
"In line with previous reports that hydroxyzine can inhibit hERG potassium channels with IC 50 values ranging from 0.62 mumol/L down to 0.16 mumol/L, (Sakaguchi etal."
28480041