IndraLab

Statements


USP14 activates ATPase. 2 / 2
| 2

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"A series of studies have demonstrated that Ubp6 and USP14 enhances the ATPase activity of proteasome and opens the 20S gate upon treatment with ubiquitin, ubiquitin protein conjugate or active site directed probes, such as ubiquitin aldehyde (Ubal) or ubiquitin vinyl sulfone (UbVS) (XREF_FIG A, right bottom panel) [XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR]."

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"Usp14 and Ubp6 can enhance the ATPase activity of the proteasome and partially open the CP gate [52,56-58]."