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USP18 inhibits STING1. 1 / 1

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"USP18 deficiency or knockdown of USP20 resulted in enhanced K48 linked ubiquitination and accelerated degradation of STING, and impaired activation of IRF3 and NF-kappaB as well as induction of downstream genes after infection with DNA virus HSV-1 or transfection of various DNA ligands."

27801882

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IndraLab

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USP18 inhibits STING1. 1 / 1

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