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Pimozide decreases the amount of USP1. 2 / 2

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"Interestingly, Pimozide promoted ID1 degradation, decreased USP1 levels, and caused a dose dependent inhibition of K562 cell growth in vitro with induction of apoptosis (XREF_FIG), though at a higher drug concentrations as compared to SJB2-043."

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"Importantly, pimozide lowered USP1 levels, triggered ID1 degradation and inhibited K562 cell growth in vitro and in vivo (Mistry et al., 2013)."

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Pimozide decreases the amount of USP1. 2 / 2

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