IndraLab

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"This result indicates that upregulation of USP46 inhibits tumor proliferation and growth.In contrast, we used two USP46-specific short hairpin RNA (shUSP46-1, shUSP46-2) plasmids to reduce USP46 expre[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Our data indicate that USP46 represses RCC tumor progression via the inhibition of the AKT signaling pathway."

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"In addition, USP46 functions as an MST1 DUB, enhancing MST1 kinase activity to inhibit tumor development and metastasis."