IndraLab

Statements

PDGFR activates COPS6. 3 / 3
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reach
"These results suggest that PDGFR mediates PDGF-induced up-regulation of CSN6 in PASMCs.Next, we examined whether activation of PDGFR mediates down-regulation of β-TrCP in PDGF-stimulated PASMCs."
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eidos
"This indicated that up-regulation of CSN6 by PDGFR / PI3K / Akt signaling promotes beta-TrCP degradation , which , in turn , stabilizes the cell cycle protein Cdc25A and results in PASMC proliferation ."
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"These results indicate that PDGFR mediate PI3K/Akt signaling pathway activation in PASMCs treated with PDGF.To examine whether activation of PDGFR mediates PDGF-induced up-regulation of CSN6 in PASMCs[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
30180991