IndraLab

Statements


USP9X activates ethanol. 2 / 2
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"Stressed rats received the second footshock in a familiar (FAM, same IA box as the first footshock) or novel context (NOV, single-chambered apparatus); the FAM paradigm more effectively increased alcohol drinking in males and the NOV paradigm in females."

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"In contrast, in males, FAM stress more robustly promoted ethanol intake and preference with PTSD-like fear overgeneralization , interpreted from increased avoidance of dark compartments in an unfamiliar shuttle box and EPM."