IndraLab

Statements


DNAJA1 inhibits ATXN3. 2 / 2
| 2

reach
"An overexpression of HSP40 and HDJ -2 suppressed ataxin-3 and ataxin-1 aggregation in vitro [XREF_BIBR, XREF_BIBR], but not in huntingtin exon 1 overexpressing cell lines [XREF_BIBR]."

reach
"The validity of this approach was confirmed by recent data that the overexpression of human Ydj1 homologs HDJ-1 and HDJ-2 in mammalian cells suppressed the aggregation and toxicity of ataxin-3 with expanded polyglutamine tract [14]."