IndraLab

Statements


USP11 activates PPP1CA. 3 / 3
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"USP11 promoted tumor growth and metastasis in CRC via the ERK and MAPK pathway by stabilizing PPP1CA, suggesting USP11 is a potential prognostic marker."

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"USP11 is involved in the development and progression of multiple tumors XREF_BIBR - XREF_BIBR, and we have found that USP11 could promote CRC by stabilizing PPP1CA through deubiquitination XREF_BIBR."

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"USP11 promotes colorectal cancer growth and metastasis by stabilizing PPP1CA, activating the ERK/MAPK pathway, and insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) signaling (151), and interacting with nuclear factor 90 (NF90) to promote HCC proliferation and metastasis (152)."