IndraLab

Statements



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"Thus, by causing membrane depolarization of the infected host, Cam1 mediates an abortive infection defence that protects the population rather individual bacterial cells."

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"The CRISPR effector Cam1 mediates membrane depolarization for phage defence."

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"We believe that the nuclease activity of Cas10 provides a direct attack on the phage DNA that complements the membrane depolarization caused by Cam1 to effectively inhibit the final stages of infection."