IndraLab

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USP20 increases the amount of YAP1. 5 / 5
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"Further analysis revealed that USP20 directly regulated the expression of YAP1 and its downstream target genes connective tissue growth factor and cysteine-rich angiogenic inducer 61."
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"Overexpression of USP20 upregulated YAP1 expression."
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"USP20 overexpression in BC cells significantly increased YAP1 expression, whereas treatment with si-USP20 decreased YAP1 expression (Fig.S1A)."
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"USP20 knockdown in BC cells significantly decreased YAP1 expression, whereas YAP1 overexpression reversed this effect (Fig.S3)."
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"USP20 knockdown significantly decreased the protein levels of YAP1, whereas MG132 treatment diminished this effect (Fig. 4C)."
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