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GDF15 binds KCNB1. 2 / 2

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"Taken together, our observations suggest that the effect of GDF15 on Kv2.1 expression may be developmentally regulated and associated with neuronal maturation."

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"Thus we used TGFβR1 (ALK5) inhibitors (LY364947, SB431542 and PP1) and TGFβR1/TGFβR2 dual inhibitors (PP2 and LY2109761) to determine whether the effect of GDF15 on Kv2.1 expression was associated with the TGFβR1–TGFβR2 heterodimer complex [ xref ]."

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GDF15 binds KCNB1. 2 / 2

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