IndraLab

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USP3 activates USP3. 2 / 2
| 2

reach
"Although we observed the existence of cytoplasmic USP3 even without LPS stimulation in USP3‐expressing THP‐1 cells, possibly due to the overexpression of USP3, LPS pretreatment still increased the amount of cytoplasmic USP3 in these cells (Fig EV5C), indicating that LPS‐pretreatment induces the cytoplasmic retention of both endogenous and exogenous USP3 in THP‐1 cells."

reach
"miR-224-5p downregulation or USP3 overexpression significantly increased USP3 ( Fig. 4 E, F), confirming that USP3 was downstream of miR-224-5p."