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UCHL5 activates SMAD7. 1 / 1

1 |

"Here, we report a novel interaction between smads and ubiquitin c-terminal hydrolase uch37, a deubiquitinating enzyme that could potentially reverse smurf-mediated ubiquitination. In gst pull down experiments, uch37 bound weakly to smad2 and smad3, and bound very strongly to smad7 in a region that is distinct from the -py- motif in smad7 that interacts with smurf ubiquitin ligases."

16027725

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IndraLab

Statements

UCHL5 activates SMAD7. 1 / 1

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