IndraLab

Statements


USP13 inhibits MDM2. 3 / 3
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"USP13 negatively regulates MDM2 through K63-linked ubiquitination."

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"Taken together, this data indicates that over-expression of USP13 causes the reduction and inhibition of MDM2 and thus promotes the senescence of cells."

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"The degradation of MDM2 caused by USP13 was prevented by the proteasome inhibitor MG132."