IndraLab

Statements

USP37 deubiquitinates SNAI1. 9 / 10
1 | 9
reach
"Studies have shown that PLAGL2 can activate the transcription of the deubiquitinating enzyme USP37 that deubiquitinates and stabilizes Snail family transcriptional repressor 1 (Snail1), finally fostering Snail1-mediated cell proliferation [62]."
37174714
reach
"Our studies demonstrate that a deubiquitinating enzyme (DUB) family member, USP37, can deubiquitinate Snail and prevent degradation of Snail."
31998374
reach
"USP37 deubiquitinates Snail protein, prevents the degradation of Snail, and stabilizes the initially unstable Snail protein."
34405018
reach
"USP37, a member of the deubiquitinase family, can deubiquitinate snail and prevent their degradation, thereby promoting the migration of LC cells."
37795365
reach
"Studies have shown that PLAGL2 can activate the transcription of the deubiquitinating enzyme USP37 that deubiquitinates and stabilizes Snail family transcriptional repressor 1 (Snail1), finally fostering Snail1-mediated cell proliferation [62]."
37174714
reach
"Wu et al. reported that PLAGL2 promoted the proliferation and migration of gastric cancer cells through ubiquitin-specific protease 37 (USP37)-mediated deubiquitylation of the Snail1 protein ."
38689092
reach
"USP13, USP29, and USP37 were reported to promote the metastasis of GC by deubiquitinating and stabilizing Snail [35,36,54,59]."
36497313
reach
"Subsequent sub-screening identified 23 DUBs that interact with SNAI1, out of which USP29, USP36, and USP37 upregulate and reduce polyubiquitination of the SNAI1 protein."
| PMC
reach
"Microarray analysis of total RNA isolated from stable PLAGL2 knockdown (SGC7901-shRNA) and SGC7901 NC cells elucidated three differentially expressed DUBs, of which only USP37 directly interacted and significantly diminished the ubiquitination of SNAI1."
| PMC