IndraLab

Statements


USP39 inhibits ETS2. 6 / 6
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"USP39 Represses the Transcriptional Activity of ETS2 Partly by Suppressing Its Nuclear Localization."

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"This indicates that USP39 strongly suppresses the nuclear localization of ETS2."

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"This result clearly suggests that USP39 antagonizes the transcriptional activity of ETS2, which may be partly due to the reduced nuclear localization caused by the deubiquitination of ETS2."

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"Interestingly, however, USP39 significantly suppresses the transcriptional activity of ETS2."

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"USP39 Interacts with and Suppresses Transcriptional Activity of ETS2."

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"USP39 suppressed the transcription activity of ETS2 by approximately 72.8%, while OTUD7A and OTUD7B increased the transcription activity of ETS2 by approximately 55.2% and 68.5%, respectively."