IndraLab

Statements

MTOR increases the amount of OTUB1. 5 / 5
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"MTOR inhibition prevents Otub1 protein expression and maintains GRAIL, resulting in diminished cell proliferation."
19414743
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"Inhibition of mTOR activity is sufficient to block Otub1 protein expression and maintain GRAIL, resulting in diminished cell proliferation."
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"In addition, the mTOR pathway upregulates OTUB1 expression in CD4 T cells."
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"Blocking mTOR prevents Otub1 protein expression and maintains GRAIL expression, which inhibits T cell proliferation."
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"Inhibition of mTOR, even in the presence of phosphorylated STAT5 and Akt, blocked Otub1 protein expression and maintained GRAIL expression, resulting in the inhibition of cell proliferation."
19414743