IndraLab

Statements

KCNMA1 activates endoplasmic reticulum. 5 / 5
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"Taken together, the results shown are consistent with a model whereby the delivery of SLO and SLS through adhering GAS induces ER stress."
24439371
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"The facts that host cell intactness was essential to observe sil activation and that hemolysin toxins were involved, together with the report that SLO triggers ER stress, hinted at the involvement of the latter process."
25136516
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"Non BK channel activated T9 cells display normal mitochondria (white arrows) and normal ER (black arrows)."
19247476
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"Ultrastructural analysis confirms that the mitochondria and the ER are targeted by sustained BK channel activation."
19247476
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"Here, we were able to disengage these events and show that ER stress triggered by the delivery of SLO and SLS via the adhering GAS is a distinct step in the above mentioned chain of cellular events that creates a microenvironment promoting GAS sensing and growth."
24439371