IndraLab

Statements

KCNMA1 activates endoplasmic reticulum. 6 / 6
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"Non significant differences were observed in the ER staining patterns for the cells treated with streptolysin-O (SLO), which selectively permeabilized the cell membrane, or with saponin, which generally permeabilized both the cell and the ER membranes (XREF_FIG)."
19021758
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"Ultrastructural analysis confirms that the mitochondria and the ER are targeted by sustained BK channel activation."
19247476
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"Taken together, the results shown are consistent with a model whereby the delivery of SLO and SLS through adhering GAS induces ER stress."
24439371
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"Non BK channel activated T9 cells display normal mitochondria (white arrows) and normal ER (black arrows)."
19247476
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"Here, we were able to disengage these events and show that ER stress triggered by the delivery of SLO and SLS via the adhering GAS is a distinct step in the above mentioned chain of cellular events that creates a microenvironment promoting GAS sensing and growth."
24439371
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"The facts that host cell intactness was essential to observe sil activation and that hemolysin toxins were involved, together with the report that SLO triggers ER stress, hinted at the involvement of the latter process."
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