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USP18 inhibits IFNAR1 recruitment. 1 / 1
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eidos
"USP18 is modeled as pre-bound to IFNAR2 ( i.e ., before IFN stimulation ) and reduces IFNAR1 recruitment into the ternary complex by increasing k-4 ( see Long Time Deactivation via USP18 Regulates Receptor Complex Stability to Achieve Absolute Discrimination ) ."