IndraLab

Statements


OTUD5 inhibits TRAF3. 7 / 8
1 | 5 2

sparser
"231 DUBA also targets and inhibits TRAF3 by cleaving its K63-linked polyubiquitin chains."

reach
"In the study showing that OTUD5 suppresses the type I interferon (IFN-1) production, the proposed mechanism is that OTUD5 antagonizes the TRAF3 signaling (21)."

reach
"TRAF3 activation is negatively regulated by SOCS3 and DUBA."

reach
"TRAF3 activation is inhibited by SOCS3 and DUBA and TRAF 6 is targeted by numerous inhibitors including A20, USP4, CYLD, and others [73,74]."
| PMC

sparser
"TRAF3 are inhibited by DUBA, OTUB1 and UCHL1 that specilally remove TRAF3 K63‐linked ubiquitination."

reach
"Upregulated miR-210 could inhibit the expression of its target gene DUBA that is as the inhibitor of TRAF3 ( Fig. 5 )."

reach
"TRAF3 are inhibited by DUBA, OTUB1 and UCHL1 that specilally remove TRAF3 K63‐linked ubiquitination."