IndraLab

Statements

P5091 inhibits cell growth. 3 / 3

| 3

reach

"P5091 significantly inhibited cell growth of ovarian cancer, 19 oesophageal cancer 15 and colorectal cancer 20 in vitro and in vivo."

33129231

➶

reach

"P5091 inhibits human MM cell growth in vivo and prolongs survival in the MM.1 S MM xenograft mouse model."

22975377

➶

reach

"In MM cells, the concurrent use of the NEK2 inhibitor INH1 and P5091 markedly impedes cell growth and overcomes NEK2-related and inherent BTZ resistance by modulating the NF-κB and PP1α/AKT pathways [175]."

38702734

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

P5091 inhibits cell growth. 3 / 3

INDRA sources:

Databases

Reading