IndraLab

Statements

7,9-dihydro-1H-purine-2,6,8(3H)-trione inhibits NLRP3. 7 / 7
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"Doliroside A attenuates monosodium urate crystals induced inflammation by targeting NLRP3 inflammasome."
25064339
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"MiR-223-3p and miR-22-3p inhibit monosodium urate induced gouty inflammation by targeting NLRP3."
33650318
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"CAPE suppresses uric acid crystal induced NLRP3 inflammasome activation in bone marrow derived primary macrophages."
27934918
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"Oral administration of CAPE prevents uric acid crystals induced gout in mice by blocking NLRP3 inflammasome activation."
27934918
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"The deleterious effects of urate are primarily attributed to its ability to trigger the formation of reactive oxygen species (ROS) and activate NLRP3."
27209322
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"MiR-223-3p inhibits inflammation and pyroptosis in monosodium urate induced rats and fibroblast like synoviocytes by targeting NLRP3."
33608866
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"Likewise, animal experiments have found that uric acid lowering drugs (such as allopurinol and quercetin) can reduce uric acid and blood lipid levels, inhibit the activation of NLRP3 inflammasomes, and prevent kidney damage caused by STZ."
33692782