IndraLab

Statements


| 1 2

sparser
"IMO-8400 is a second-generation oligonucleotide antagonist that inhibits TLR7, TLR8 and TLR9 as well as disease progression of SLE and psoriasis in animal models ( xref – xref )."

eidos
"Furthermore , the antagonist abolished the Tlr7 / 9-enhanced LDL uptake ."
| PMC

sparser
"The use of A151, an oligonucleotide described as a TLR antagonist inhibiting TLR7 and, to a lesser extent, TLR9 did not inhibit IFN-α/β induction by UV-BTV, indicating that UV-BTV activates IFN-α/β production via a TLR7/8-independent mechanism."