IndraLab

Statements

PSMD14 activates Cell Survival. 4 / 4
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"PSMD14 siRNA knockdown in another human cell line, hTERT immortalized human mammary epithelial cell line hTERT-HMEC1, caused a dramatic reduction of cell viability (36% viability)."
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"Conversely, ectopic POH1 expression substantially potentiated tumour cell survival in detached culture conditions (XREF_FIG)."
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"To more specifically test for any requirement of the zinc metalloproteinase motif of Poh1 to support cell viability and proteasome function, we developed a RNAi complementation strategy."
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"We studied the oncogenic function of POH1 in solid tumors; knockdown of POH1 expression in QGY-7701, EC109, and HCT116 cells decreased cell viability and induced apoptosis."
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