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BAP1 activates MCRS1. 3 / 4
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"BAP1 also contributes to chromosome stability by binding the microspherule protein 1 (MCRS1) which plays an essential role in spindle assembly XREF_BIBR."
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"In the absence of de novo protein synthesis, the half-life of endogenous MCRS1 protein was much shorter in the BAP1 depleted cells than that in control cells, further suggesting that BAP1 regulates MC[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"To determine whether BAP1 increases MCRS1 by extending its half-life, the protein level of MCRS1 was monitored after treatment with the protein synthesis inhibitor cycloheximide (CHX)."
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