IndraLab

Statements


3 | 2

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"Moreover, BAP1 -KO had a negligible effect on cell proliferation, whereas CAMK2D / BAP1 -DKO reduced cell proliferation, suggesting that an emerging BAP1-CAMK2D axis might play a critical role in the tumor growth of BAP1 -deficient MMe cells."

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"Therefore, targeting the BAP1-CAMK2D (CAMKII delta) signaling axis is a promising therapeutic approach for most MMe cases and BAP1 tumor predisposition syndrome."

No evidence text available