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USP2 inhibits NF-kappaB basal. 1 / 1

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"The ubiquitin #specific proteases system 2 ( USP2 ) stabilizes the ubiquitin-E3-ligase ITCH and lowers NF-kappaB basal activity , which leads to reduced c-FLIP mRNA production ; proteasomal degradation of c - FLIP isoforms is also elevated by its negative regulator proteasome ITCH [ 31 ] ."

32352084

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USP2 inhibits NF-kappaB basal. 1 / 1

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