IndraLab

Statements

OTUD5 activates ferroptosis. 5 / 5
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"These findings suggest that OTUD5, through GPX4 stabilization, protects renal tubular cells from I/R-induced ferroptosis."
38110369
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"We then identified ovarian tumor domain-containing 5 (OTUD5) as a GPX4-interacting protein that promotes resistance to ferroptosis during I/R by stabilizing GPX4 expression."
38110369
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"These data implied that the protective effect of OTUD5 against I/R‐induced myocardial injury may be related to GPX4 dysfunction‐mediated ferroptosis."
37552043
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"We further investigated whether OTUD5 protected renal tubular cells from H/R-induced ferroptosis by stabilizing GPX4."
38110369
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"Specific targeting of OTUD5 may mitigate I/R‐induced ferroptosis and cardiac injury."
37552043