IndraLab

Statements

USP20 activates Cell Survival. 5 / 5
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"Knockdown of USP20 and p62 in HeLa cells decreases cell viability and number while increasing the expression of cleaved caspase-8, caspase-3 and PARP (153)."
36969062
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"We observed that USP20 depletion reduced the cell viability upon the treatment of erastin, which could be rescued by Ferr‐1, suggesting that the mechanism is specific in cell ferroptosis (Figures 2F, G and S2G)."
38124786
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"Furthermore, reconstitution of WT USP20 but not USP20-4 mut rescued the cell viability after UV treatment and restored UV or HU induced intra-S-phase checkpoint."
25355518
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"Consistent with the USP20‐knockdown results, GSK2643943A decreased the cell viability and increased erastin‐induced viability inhibition and increased ferrous iron levels and lipid ROS levels, while decreased the GSH levels in Huh‐7 cells (Figures 3A–G)."
38124786
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"USP20 depletion also reduced the cell viability upon the treatment of erastin, which could be recovered by Ferr‐1, suggesting that the mechanism is specific in cell ferroptosis."
38124786