IndraLab

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SCN5A activates UDB. 2 / 2
| 2

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"Propafenone produced more left shift of steady-state inactivation and slower recovery from inactivation in R1193Q compared with WT.Conclusion: A common SCN5A polymorphism R1193Q enhances UDB by propafenone and predisposes the patients to drug-induced BrS with PIP treatment."

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"Conclusion : A common SCN5A polymorphism R1193Q enhances UDB by propafenone and predisposes the patients to drug induced BrS with PIP treatment."