IndraLab

Statements

MiR-542-3p decreases the amount of OTUB1. 3 / 3
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"Expression of OTUB1 is repressed by miR-542-3p in esophageal cancer cells."
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"For example, miR-542-3p expressions are greatly down-regulated in esophageal cancer, and miR-542-3p can inhibit the migration and aggressiveness of esophageal cancer cells by inhibiting OTUB1 expression [17]; in osteosarcoma, miR-542-3p can curb cell proliferative, migrative and aggressive abilities via targeting ILK [18]; in ovarian cancer, miR-542-3p can target CDK14 to inhibit tumorigenesis [19]; in bladder cancer, importantly, miR-542-3p expression is significantly impaired, and this miRNA can inhibit the viability of BC cells [20]."
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"Ectopic expression of miR-542-3p which inhibits OTUB1 expression, attenuates proliferation, migration, and invasion while promoting apoptosis in colorectal cancer cells (Yuan et al., 2017)."
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