IndraLab

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OTUB1 leads to the deubiquitination of MDM2. 1 / 1
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"Examples for DUBs that might antagonize E4 dependent polyubiquitylation are USP47, a regulator of Base Excision Repair (BER) that controls DNA polymerase beta and OTUB1, which mediates DNA damage dependent deubiquitylation of p53 and MDM2 in the cytoplasm."