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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

E3_Ub_ligase inhibits USP9X. 2 / 2

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"SCF (Slimb) as an E3 that antagonizes FAF in regulating PAR-1."

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"Therefore, phosphorylation at Ser155, Ser159 and Thr163 not only drives the binding of E3 ubiquitin-ligases such as SCF beta-TrCP, SCF Fbw7 or Trim17, but also disrupts the binding of the deubiquitinase USP9X (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...