IndraLab

Statements

USP7 activates Hedgehog. 4 / 5
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reach
"We next examined whether Usp7 synergizes with GMPS to positively regulate Ci and Hh signaling."
26120032
reach
"We next examined whether Usp7 synergizes with GMPS to positively regulate Ci and Hh signaling, Double knockdown of usp7 and gmps caused a more dramatic decrease of ptc-lacZ expression than usp7 or gmps single knockdown (XREF_FIG)."
26120032
reach
"In sum, Usp7 modulates Ci and Hh signaling through its interaction with Ci and its deubiquitinase activity.We next determined whether Usp7 stabilizes Ci through deubiquitinating Ci using a cell based [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26120032
reach
"In sum, Usp7 modulates Ci and Hh signaling through its interaction with Ci and its deubiquitinase activity."
26120032