IndraLab

Statements

USP7 activates Hedgehog. 4 / 5
| 4
reach
"Since our previous data have demonstrated that Usp7 positively regulates Hh pathway in Drosophila and mammalian cells [8] , it is fruitful to investigate whether Usp7 governs MB formation through trig[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28137592
reach
"In sum, Usp7 modulates Ci and Hh signaling through its interaction with Ci and its deubiquitinase activity."
26120032
reach
"We next examined whether Usp7 synergizes with GMPS to positively regulate Ci and Hh signaling, Double knockdown of usp7 and gmps caused a more dramatic decrease of ptc-lacZ expression than usp7 or gmps single knockdown (XREF_FIG)."
26120032
reach
"In addition, it has been observed that Usp7 forms a complex with GMPS to promote Hedgehog pathway activity [21]."
37759779