IndraLab

Statements

USP14 inhibits cell growth. 4 / 4
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"USP14 downregulation by miR-124a led to reduced cell growth, stemness and enhanced gefitinib sensitivity [12]."
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"USP14 down-regulation inhibited MCL cell growth in vivo."
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"Since we have observed that inhibition or knockdown of USP14 inhibited cell growth in LNcap cells, we further investigated whether USP14 inhibition or silence induces cell death of LNcap cells by measuring Annexin V-FITC/PI-positive cells with flow cytometry and by measuring PARP cleavage and p53 and Bax protein expression with western blot analyses."
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"We previously confirmed that a specific USP14 and UCH37 inhibitor b-AP15 4 inhibited tumor cell growth and induced apoptosis and in vitro (data not shown)."
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