IndraLab

Statements


MiR-31 decreases the amount of BAP1. 3 / 3
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"In this study, we identified BAP1 as a direct target gene of miR-31 and showed that miR-31 inhibited BAP1 expression."

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"We also detect the mRNA and protein expression level of BAP1, tumors with BAP1 plasmid transfected group exhibited higher BAP1 mRNA and protein expression compared with the control group, suggesting that BAP1 plasmid overexpression could rescue the expression of BAP1 suppressed by miR-31."

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"As anticipated, the expression of the BAP1 protein was significantly reduced by the introduction of miR-31, whereas the miR-31 inhibitor significantly increased the BAP1 protein levels in A549 cells."