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USP22 inhibits SOX2. 1 / 2

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"Moreover they found USP22 represses the SOX2 promoter in order to control the embryonic stem cell transition from self-renewal to differentiation [XREF_BIBR] Therefore, not only is SOX2 an essential stem cell marker but its suppression is mandatory for cellular differentiation."

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USP22 inhibits SOX2. 1 / 2

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