IndraLab

Statements

Pristimerin binds USP50 and Cys53. 1 / 1

| 1

reach

"We further identify that PM binds the Cys53 site of deubiquitinase USP50 through the Michael-acceptor and blocks the binding of USP50 to PYCARD/ASC, thereby reducing USP50-mediated cleavage of K63-linked ubiquitin chains of PYCARD/ASC."

37647255

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Pristimerin binds USP50 and Cys53. 1 / 1

INDRA sources:

Databases

Reading