IndraLab

Statements


USP13 ubiquitinates STING1. 4 / 4
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"Nevertheless, USP13 deficiency enhances antiviral responses through deubiquitinating stimulator of interferon (STING) [56]."

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"Consistently, reconstitution of USP13 but not USP13 (AE) into Usp13 m/m MEFs inhibited HSV-1-induced ubiquitination of STING (XREF_FIG)."

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"USP13 negatively regulates antiviral responses by deubiquitinating STING."

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"These data together suggest that USP13 inhibits the recruitment of TBK1 to STING by deubiquitinating STING."