IndraLab

Statements

USP10 activates Cell Survival. 6 / 6
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"Silencing USP10 alone decreased cell viability by ~40% in MIA PaCa-2 cells and by ~48% in AsPC-1 cells."
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"USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination."
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"The MTS results also showed that pharmacological inhibition of USP10 with Spautin-1 notably decreased the cell viability of CML cells."
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"Under the treatment of PDGF-BB, USP10 inhibition decreased cell viability in VSMCs (Fig. 2D)."
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"The inhibition or knockdown of USP10 decreased the cell viability by blocking the cell cycle transition from G1 to S phase in VSMCs."
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"Thus, USP10 and p62 promote cell survival by reducing the amount of cytotoxic ubiquitinated protein monomers and oligomers."
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