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USP10 activates Cell Survival. 3 / 3

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"Thus, USP10 and p62 promote cell survival by reducing the amount of cytotoxic ubiquitinated protein monomers and oligomers."

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"The MTS results also showed that pharmacological inhibition of USP10 with Spautin-1 notably decreased the cell viability of CML cells."

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"Furthermore, depletion of USP10 in lung cancer cells causes decreased apoptosis and increased cell survival upon treatment with DNA damaging agents."

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IndraLab

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USP10 activates Cell Survival. 3 / 3

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