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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP10 activates Cell Survival. 3 / 3

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"Thus, USP10 and p62 promote cell survival by reducing the amount of cytotoxic ubiquitinated protein monomers and oligomers."

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"The MTS results also showed that pharmacological inhibition of USP10 with Spautin-1 notably decreased the cell viability of CML cells."

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"Furthermore, depletion of USP10 in lung cancer cells causes decreased apoptosis and increased cell survival upon treatment with DNA damaging agents."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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USP10 activates Cell Survival. 3 / 3

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