IndraLab

Statements

USP37 activates epithelial to mesenchymal transition. 15 / 15
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"These data confirm that USP37 mediates breast cancer stem-like properties , cell invasion and EMT via the Hh pathway ."
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"USP37 is a modulator of the epithelial-mesenchymal transition and metastasis ."
| PMC
eidos
"USP37 knockdown inhibits stemness , cell invasion and EMT via Hedgehog signaling pathway in breast cancer ."
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"Snail protein is an essential positive regulator of EMT, which is upregulated by USP37."
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"On the contrary, upregulation of USP37 promoted EMT, migration and invasion."
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"In order to understand the mechanism of USP37-induced EMT and stemness via the Hh pathway, we treated MCF-7 cells with PM."
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"Therefore , USP37 promotes EMT via the SHH pathway , and the signalling outcomes are determined by the balance of activated and inhibitory GLI1 proteins [ 39 ] ."
| PMC
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"The knockdown of USP37 could inhibit the stemness , cell invasion and EMT via downregulation of Hedgehog pathway ."
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"Knockdown of USP37 expression hampered cell invasion , stemness , EMT and also resulted in the drug sensitivity to cisplatin ."
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"Further studies indicated that USP37 knockdown could inhibit the stemness, cell invasion and EMT in breast cancer via downregulation of Hh pathway."
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"Therefore, USP37 promotes EMT via the SHH pathway, and the signalling outcomes are determined by the balance of activated and inhibitory GLI1 proteins [39]."
| PMC
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"Further studies indicated that USP37 knockdown could inhibit the stemness, cell invasion and EMT in breast cancer via downregulation of Hh pathway."
30482232
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"The knockdown of USP37 could inhibit the stemness, cell invasion and EMT via downregulation of Hedgehog pathway."
30482232
eidos
"USP37 knockdown inhibits stemness , cell invasion and EMT via Hedgehog signaling pathway in breast cancer ."
| PMC
reach
"In contrast, USP37 upregulation promotes EMT, migration, and invasion [39]."
| PMC