IndraLab

Statements

USP33 binds Integrins. 10 / 10
| 2 8
sparser
"In addition, we detected the effect of USP33-integrin α6 regulation on cell metastasis in vivo."
39589547
sparser
"USP33 binds and stabilizes integrin α6 through deubiquitination."
39589547
sparser
"The result showed that USP33 could interact with integrin α6 and β4 (Fig.  xref B)."
39589547
sparser
"Altogether, these results indicate that USP33 could bind and stabilize integrin α6 through deubiquitination."
39589547
sparser
"As described above, USP33 could bind and deubiquitinate integrin α6 to stabilize its expression; it is reasonable to infer that the USP33-integrin α6 axis plays an essential role in ESCC cell migration on laminin."
39589547
reach
"The interaction between USP33 and integrins was detected by immunoprecipitation, and the deubiquitination was performed by deubiquitination assay."
39589547
reach
"USP33 binds and stabilizes integrin alpha6 through deubiquitination."
39589547
sparser
"The interaction between USP33 and integrins was detected by immunoprecipitation, and the deubiquitination was performed by deubiquitination assay."
39589547
sparser
"Mechanistically, USP33 can interact with integrin α6 and subsequently promote its deubiquitination and stabilization."
39589547
sparser
"These findings are the first to describe that USP33 promoted laminin-dependent cell migration by stabilizing integrin α6, which provides an insight into the mechanistic roles of USP33-integrin α6 axis in ESCC metastasis."
39589547