IndraLab

Statements

PPP3R1 activates HCN4. 1 / 1

| 1

reach

"This HCN4 TM-replacement preserved cAMP potentiation but augmented the magnitude of autoinhibition by the unliganded CNB fold; it moreover disrupted open-state trapping and Quick Activation so that autoinhibition became the dominant mechanism contributed by the C-terminal region to determine kinetics."

32146488

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

PPP3R1 activates HCN4. 1 / 1

INDRA sources:

Databases

Reading