IndraLab

Statements

USP33 deubiquitinates PRKN on K435. 4 / 4
| 4
reach
"USP33 prefers to remove K6, K11, K48 and K63 linked ubiquitin conjugates from PRKN, and deubiquitinates PRKN mainly at Lys435."
31432739
reach
"USP33 Deubiquitinates K63-Linked Ubiquitin on Parkin at Lys435."
36831318
reach
"USP33 deubiquitinates Lys435 of parkin and inhibits its mediated clearance of damaged mitochondria."
36260224
reach
"Different from USP30 which regulates substrates of Parkin, USP33 can directly and selectively deubiquitinate Parkin at Lys435 and preferentially remove K6, K11, K48, and K63-linked ubiquitin conjugates from Parkin."
34804365